Sydney are hopeful of regaining key players for this weekend's derby against GWS as they plot to bounce back from their biggest loss in recent memory.

Close to 1000 games of AFL experience watched on as Geelong handed the Swans a 93-point hammering - the biggest defeat of John Longmire's 13-year coaching tenure - in the grand final rematch at Kardinia Park last weekend.

Veteran forward Lance Franklin (knee) and important defenders Dane Rampe (neck) and Tom McCartin (concussion) have missed the past two weeks and already one of the youngest lists in the AFL, the Swans cried out for their experience in round six.

But co-captain Callum Mills confirmed the trio are a chance for Saturday's clash against the Giants, where pride is once again on the line.

"They're not ruled out, we'll see how this weekend goes but we can't say they're definitely playing as well," Mills said.

"We'll see how this week pans out and what happens there."

Ruckman Tom Hickey is in line for his first game of the season after shaking off a calf injury and making his return via the VFL last week but there is still no update on Paddy McCartin, who is recovering from the 10th concussion of his AFL career.

"(Hickey) will put his hand up for selection," Mills said.

"Paddy's one of my good mates so my care goes out to Paddy. His health is the main priority at this moment and we're all behind him."

The Swans meet a GWS side battling personnel issues of their own, but they could welcome veteran Phil Davis back for his first senior game of the year.

"He put his hand up. He's, I think he's still a bit sore, though," Giants captain Toby Greene said.

"He hasn't had a whole lot of footy in the last six to eight weeks so it's sort of a wait and see at training."

All-Australian defender Sam Taylor (hamstring) and foundation Giant Adam Kennedy (knee) became the latest additions to the GWS casualty ward last weekend, while Callan Ward misses through suspension as the latest victim of the AFL's tackle crackdown.

"It's a massive blow, no doubt (Taylor) probably is the best key defender in the competition," said Greene.

"Adam Kennedy as well has done his ACL, which is super disappointing.

"Both frustrating injuries and part of footy but it'll give opportunities to a few others as well this week.

"We still feel like we've got a bloody good team."

Greene, known for playing a passionate brand of footy, insisted players knew where the line was after the usually scrupulous Ward found himself sanctioned for his sling tackle on Brisbane's Lachie Neale.

"We all know that if you put yourself in that situation, you're going to be in trouble," Greene added.

"Everyone knows what it is and isn't acceptable. It's probably changed in the last six weeks but you do know."