Injured Australian opener Usman Khawaja is unlikely to bat on the final day of the fourth Test against India.

Scans have not shown any conclusive injury after Khawaja was helped from the field by the team doctor following a catching attempt gone wrong on the boundary on Sunday.

"He did have a scan, which is standard procedure. The imaging did not reveal anything conclusive," an Australian team spokesman said.

"He has soreness in his left lower leg, just below the knee on the outside of the lower leg."

The in-form opener had a long conversation with Australia coach Andrew McDonald before the start of play and tried running slowly on Monday's fifth and final day of the Test.

Khawaja will continue to be assessed again by team medicos but it is understood he is only a chance to bat again if Australia become desperate to save the match.

He was off the ground for almost two hours on Sunday as India piled on 571.

Australia had to face six overs before stumps on Sunday but No.11 Matt Kuhnemann was sent out as a nightwatchman to open with Travis Head instead of Khawaja.

When Khawaja went down, the 36-year-old appeared to grab his knee.

It would be a mighty blow for Australia if Khawaja is unable to bat, after his marathon 180 in the first innings, one of the finest knocks of his career.

After having a tough first Test against India, Khawaja has hit back to be the leading run-scorer on either team in the series with 333 at 47.57.

Australia's hopes of levelling the series 2-2 seem doomed with only India having an outside chance of winning the Test on the final day.

But India allrounder Axar Patel said "anything can happen" when asked if his team believed they could secure an unlikely victory and a 3-1 series result.

"If we get two or three wickets early tomorrow, they might play defensive under pressure," Patel said, translated from Hindi.